ANOVA will compare symptom severity over time within and between groups.Blood draws will be obtained pre- and posttreatment to assess predictors of treatment response and epigenetic markers of change.

for PE, with sessions separated by at least 24 hours over two weeks.The CAPS-5, the gold standard for PTSD diagnosis, will be administered and scored at baseline to confirm the diagnosis, and subsequently as the primary outcome measure at 2, 6, and 12 months, by expert administrators who will be blinded to treatment arm.Participants in each arm of the study will receive up to 10 90-minute manualized treatment sessions.-dependent protease that exerts its effects through the proteolytic cleavage of target proteins.Neuron-specific conditional deletions of calpain 1 and 2 impair long-term potentiation in the hippocampus and spatial learning.

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